NMReady adds a new dimension of access to NMR spectroscopy across all markets and to all types of users without adaptation of method or practice. The compact all-in-one NMReady will fit in virtually any location providing point of need access to NMR for any application. At the bench, on the manufacturing floor, the loading dock or in the classroom, NMReady provides access to high resolution NMR spectroscopy without the expense, complexity, or ongoing costs of traditional NMR.


Pharmaceuticals, Nutraceuticals and Biotechnology


1H and multinuclear NMR Spectroscopy (e.g., 13C, 19F, 31P) are essential tools for structural elucidation and drug discovery. Benchtop NMR spectroscopy can be useful for structural confirmation of both known synthetic drugs and natural products.

In addition to qualitative analysis, the quantitative nature of NMR spectroscopy can address a number of inquiries including:
(i) impurity profiles;
(ii) composition (e.g., composite β-lactam/β-lactamase inhibitor antibiotics);
(iii) metabolic products in bodily fluids;
(iv) reaction monitoring/kinetic profiling etc.

With a growing number of flow applications developing for benchtop NMR, these analyses can also be done on dynamic samples in dedicated benchtop reactors or larger production facilities.


Polymer Characterization

Polymer characterization is vital to ensure quality and consistency among polymeric products. Although there are many analytical methods that are used for QA/QC, NMR Spectroscopy is useful to:
(i) observe reaction completeness & uniformity;
(ii) qualify the relative composition of the structural components;
(iii) quantify the relative percentage of structural isomers;
(iv) observe the presence of stereoisomers and determine polymeric tacticity; and
(v) determine molecular weight (Mw), molecular number (Mn) and polydispersity index (PDI).

Even though this has been done on high-field instruments for years, it can be expensive, and, depending on the accessibility/availability of a spectrometer, time consuming. Given that polymer chemistry is not sample limited, and that polymer 1H NMR is often defined by broad, poorly defined peak areas and resolution and peak definition is not a large issue, this is an application ideal for study by either 1H or 19F benchtop NMR. For an example please see co-polymer composition determination.


Biodiesel Research

As biodiesel is formed through a simple transesterification, it is easily monitored and characterized by NMR Spectroscopy. This analytical technique allows easy, non-destructive evaluation of many of the components regulated in biodiesel standardization (e.g., water, alcohol, phosphorous, and glycerol content). Subsequently, the NMReady could be easily incorporated into characterization to improve workflow. NMR Spectroscopy can be used to quantify the percentage of biodiesel in composite fuel mixture. Click HERE for a biodiesel spectrum generated on the NMReady and HERE for a related blog entry.

Food Science


Relaxometry has long been used in food science to determine the solid fat content (SFC), moisture content etc.. Not only can the NMReady perform these fundamental experiments, but, in addition, the option to measure high-resolution 1D 1H NMR acquisition can provide additional invaluable information through speciation (e.g., amount of saturated and unsaturated fats, cis/trans olefin conformations, % carbohydrates). qNMR QA/QC methods are also possible to validate product claims (e.g., carbohydrate content, alcohol percentage, authenticity of the sample or the presence of adulterants). For an example, please see Detection of Soybean Adulteration in Olive Oil.

Environmental Screening

NMR methods can be useful in quantifying and speciating dissolved organic matter in earth’s atmosphere, ocean, and soil (e.g., chlorofluorocarbons, benzene, toluene, ethylbenzene & xylene (BTEX), methyl tert-butyl ether (MTBE).

Hands-on Teaching for Undergraduate Labs


Educational curricula trends are shifting towards hands-on, guided-inquiry approaches that help students obtain meaningful learning. As chemistry laboratories provide the perfect opportunity for students to supplement cognitive learning with psychomotor skills, an increasing number of analytical characterization techniques have been incorporated into procedures (e.g., UV-Vis, IR). Even though NMR is the most commonly used characterization technique in inorganic and organic chemistry, it is usually the least available to undergraduate students. As the biggest restriction to including NMR spectroscopy in laboratories is the limited accessibility of high-field NMR, the NMReady provides an easy solution. It is compact, portable and easy-to-use. Moreover, it does not require weekly maintenance and is designed to minimize damage occurred by broken NMR tubes.

Related Teaching Links:

  • More details on our teaching applications click here.
  • Ideas on how to incorporate NMReady into your laboratory curriculum, see sample experiments.
  • You can view feedback from Boston College in this video.
  • See the latest academic product brochure here.