To Decouple or Not to Decouple, That is the Question. Also….Acids.

To Decouple or Not to Decouple, That is the Question.  Also….Acids.

Acidity is something that you encounter on a daily basis, probably without even realizing it. The tangy taste of an orange (citric acid), that Vitamin C tablet you took this morning (ascorbic acid), those terrible jeans from the 80’s that you still wear (acid wash). My favourite acid is acetic acid.

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Boron NMR Spectroscopy

Boron NMR Spectroscopy

For my first blog I have decided to talk a little bit about boron because it’s a fascinating element that imparts remarkable properties to its compounds. And believe me, there are hundred of different compounds with very different properties containing boron centers. We find boron in compounds like boronic acids (A), boronic esters (B), and MIDA boronates (C), all of which are very popular in Suzuki coupling reactions to make new C–C bonds.  Another popular family of compounds containing boron are the BODIPY dyes (D). These derivatives, composed of a dipyrromethene ligand supporting a BF2 unit, are used as stable functional dyes in several fields, but their application as biomolecular labels is the most investigated by far.

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