What's the 'ism' of today? Keto-Enol Tautomerism

What's the 'ism' of today? Keto-Enol Tautomerism

Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed more here.

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'Hop' off the Diagonal: COSY spectrum of α-humulene

'Hop' off the Diagonal: COSY spectrum of α-humulene

NMR spectroscopy is by far the most useful characterization technique in organic chemistry, especially if you have to elucidate the structure or configuration of your products. Arguably, 2D experiments such as COSY, HSQC, and HMBC have simplified this task tremendously. In this post I wanted to highlight the COSY of α-humulene. 

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