Lead NMR Spectroscopy

Lead NMR Spectroscopy

For many years tetraethyl lead was used as the principal fuel additive to enhance the octane rating of gasoline. In the mid-1970s the use of this substance was reduced because of the environmental hazards of lead and because it poisons catalytic converters. Nowadays, the main application of lead metal and lead oxide is in lead-acid batteries. In this application the cathode of the cell consists of lead dioxide packed on a metal grid and the anode is composed of lead metal. The electrochemical reaction is shown in the following equation:

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Automation, Benchtop NMR and Industry

Automation, Benchtop NMR and Industry

Since it was discovered, the typical trend in NMR Spectroscopy has been towards higher field, evidenced by the rapid replacement of permanent magnets with supercons.[1]  Why?  Well, NMR Spectroscopy, of course, is one of the most information rich molecular spectroscopic techniques available, providing information of the type of nuclei, the number of those nuclei and even how they’re connected.  As you move to higher field you can immediately observe two things: 1) it’s easier to extract the aforementioned information because the resolution is better (i.e., more Hz/ppm dispersion) given the more favourable dispersion and 2) the data has inherently higher signal-to-noise ratio. 

 

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2017 Year in Review

2017 Year in Review

With great advances in areas such as metabolomics, quantitative NMR, and online analysis, 2017 was a very exciting year for NMR in general, but specifically so for Benchtop NMR! Benchtop NMR has continued to make NMR, one of the strongest characterization techniques, become a mainstream staple in teaching and research laboratories. As users realize how easy it is to incorporate the NMReady-60 spectrometers into their laboratories, they have continued to breakthrough into new and exciting applications.

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The lightest metal with a heavyweight demand: Lithium

The lightest metal with a heavyweight demand: Lithium

Before the early 1950’s lithium was an ingredient found in Seven-up®; however, after concerns by the FDA it was removed from this popular beverage. Interestingly, about the same time it was found that lithium had antipsychotic properties, but it was only approved for human consumption in the 1970’s.[1] Despite being such a simple molecule lithium carbonate is still the most effective drug for the treatment of bipolar affective disorder! We don’t hear this side of the lithium history very often. In recent years this element has become very popular and its demand has increased considerably due to its widespread use in batteries for small electronic devices such as smart phones and laptops.[2]

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Boron NMR Spectroscopy

Boron NMR Spectroscopy

For my first blog I have decided to talk a little bit about boron because it’s a fascinating element that imparts remarkable properties to its compounds. And believe me, there are hundred of different compounds with very different properties containing boron centers. We find boron in compounds like boronic acids (A), boronic esters (B), and MIDA boronates (C), all of which are very popular in Suzuki coupling reactions to make new C–C bonds.  Another popular family of compounds containing boron are the BODIPY dyes (D). These derivatives, composed of a dipyrromethene ligand supporting a BF2 unit, are used as stable functional dyes in several fields, but their application as biomolecular labels is the most investigated by far.

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#Worldbookday

I don’t know if you check out Compound Interest (@compoundchem) or not, but if you don’t you should probably consider remedying that IMMEDIATELY!  Pretty much every single time that I read it I have a “HMMMM, OHHHH, Cool! I had no idea!” moment.  Today, was no exception. They have interesting real world chemistry examples of …

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