Fast, Accurate Identification of Complex Drug Mixtures —
No NMR Expertise Required
Seized drug samples are rarely simple. Street samples typically contain a controlled substance blended with adulterants and cutting agents — mixtures of varying and often unknown complexity. Conventional methods like chromatography, IR, and UV spectroscopy rely on lengthy workflows and reference materials that fall short when composition is uncertain or standards don’t exist for new designer drugs.
Benchtop NMR paired with Wiley’s KnowItAll changes that. NMR delivers the highest wealth of structural information of any analytical technique and is uniquely suited to untargeted analysis — without destroying the sample. And with today’s highly accessible, low-maintenance benchtop NMR systems, forensic analysts can now measure seized samples rapidly, even outside traditional laboratory environments.
A Powerful Tandem: Benchtop NMR + KnowItAll
KnowItAll’s integrated, modular architecture moves logically from task to task — eliminating the friction of traditional NMR workflows. Three tools work seamlessly together: NMR data processing (ProcessIt), custom database creation (MineIt), and spectral identification through database matching (SearchIt). The result is a fast, efficient analytical environment that significantly reduces the need for specialized NMR expertise, enabling automated workflows from raw data through to final identification.
Build and Share Custom Reference Databases — Instantly
With KnowItAll’s MineIt tool, building a representative user database is fast and highly automated. Molecular structures, weights, chemical formulas, and spectral metadata are populated automatically — meaning only a common substance name is needed to complete an entry. Databases can include multiple analytical techniques per compound, can be categorized (e.g., by DEA regulation), and can be shared across an organization via cloud storage — extending the reach of your resources without duplicating effort.
Proven Across High-Stakes Applications
Pharma & Biotech — Accelerate drug development and quality assurance with confident compound identification.
Forensics & Border Control — Rapidly identify unknown street drug mixtures — directly from seized samples, with no reference materials or NMR specialist needed. Results that once required lengthy lab workflows are now available in the field.
Materials — Characterize complex materials with precision and consistency.
Flavor & Fragrance — Identify and profile compounds across complex mixtures with ease.
Nutraceuticals — Ensure product integrity and compliance with reliable, repeatable analysis.