Pharmaceuticals and Biotechnology
Improve productivity with compact NMR
1H NMR and multinuclear NMR spectroscopy are essential tools for structure elucidation and drug discovery. Developments of quantitative NMR (qNMR) can also be used to observe reaction completeness, purity, formulation, solvent removal etc. Inquire for more information about how benchtop NMR can be automated as a QA/QC tool to streamline pharmaceuticals and biotech applications.
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In addition to qualitative analysis, the quantitative nature of NMR can address a number of inquiries including:
Impurity profiles
Composition (e.g., composite beta-lactam/beta-lactamase inhibitor antibiotics)
Metabolic products in bodily fluids
Reaction monitoring/kinetic profiling at-line or on-line
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Quantification of Amyl Nitrites in Inhalant Mixtures Using Quantitative NMR (2021)
Assay of an Active Pharmaceutical Ingredient (API) in Formulated Tablets via Benchtop qNMR (2020)
Amine (R) and (S) Chirality Analyzer: Chemosensors & 19F Benchtop NMR Spectroscopy (2017)
Automatic, High-Throughput Data Processing: Illustrated through NSAIDs (2016)
Quantification of Composite beta-lactam/beta-lactamase Antibiotics (2015)
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If you’re interested in software packages that ease incorporation of your benchtop NMR, please inquire about:
Installation Qualification/Operational Qualification (IQ/OQ) software modules
Advanced User interface for optional application programmatic interface to write own pulse programs or control instrument remotely
Developments of CFR 21 Part 11 Compliance.
For more information about incorporating benchtop NMR into your daily workflow, please inquire for free sample submission, optional automation, building a database and other tools.