The Limit of Detection (LoD) and Limit of Quantification (LoQ) are analytical benchmarks that define the practical boundaries for identifying and measuring a specific analyte within a given matrix, under particular experimental conditions.

In this ever-evolving world where technology and science keep pushing into new territory, new inventions are being made and state-of-the-art validation methods are being developed. Over the last few decades, lithium-ion batteries have gained more and more traction in their uses, moving from general simple batteries used for powering your calculator or phone, to cars and trucks, and even airplanes (currently only the small ones). However, as simple as batteries may seem, a lot of work must be done behind to scenes to develop these subtle but priceless additions to our lives.

When analyzing polymers using nuclear magnetic resonance (NMR) spectroscopy, well-defined end-groups (e.g., methoxy, acrylate, vinyl) are typically desired, as these allow for a direct comparison between these end-groups and the repeating monomeric units. This provides a path for rapid and facile determination of the number of repeating units in a polymer, as well as its number-average molecular weight (Mn). Read more.

When analyzing polymers using nuclear magnetic resonance (NMR) spectroscopy, well-defined end-groups (e.g., methoxy, acrylate, vinyl) are typically desired, as these allow for a direct comparison between these end-groups and the repeating monomeric units. This provides a path for rapid and facile determination of the number of repeating units in a polymer, as well as its number-average molecular weight (Mn). Read more.

In the 19F NMR spectrum of DCBTF, we can observe the singlet resonance of the trifluoromethyl fragment at δ = −63.07 ppm. While it might not jump into your eye at first glance, please note that the carbon satellites are not centered at the "main signal", which is what we are used to from 1H NMR spectra. Read more

In the 19F NMR spectrum of DCBTF, we can observe the singlet resonance of the trifluoromethyl fragment at δ = −63.07 ppm. While it might not jump into your eye at first glance, please note that the carbon satellites are not centered at the "main signal", which is what we are used to from 1H NMR spectra. Read more

In the agrochemical industry, quantifying active ingredients containing fluorine can be simplified by using 19F benchtop NMR instead of other nuclides proton. Read more to find out how.

Fluorine-19 is one of the most popular nuclides in NMR, along with 1H, 13C and 31P. It has a relatively large chemical shift window (-300 to 400 ppm), which minimizes signal overlap even at low fields, is 100% naturally abundant, and its sensitivity is nearly as high as proton. Read more.

BODIPY dyes, which are boron difluoride compounds supported by dipyrrinato ligands, have gained recognition as being one of the more versatile fluorophores due to their superior photophysical properties.[1,2] BODIPY derivatives are used as stable functional dyes in several fields such as light harvesters, laser dyes, fluorescent switches, and biomolecular labels.[3-6] They gained popularity as biological probes due to the easy modification of the ligand framework, extension of the chromophore, and substitution of the fluorine atoms.6 Figure 1 shows some commercially available BODIPY dyes used as biological probes.

In the 19F NMR spectrum of DCBTF, we can observe the singlet resonance of the trifluoromethyl fragment at δ = −63.07 ppm. While it might not jump into your eye at first glance, please note that the carbon satellites are not centered at the "main signal", which is what we are used to from 1H NMR spectra. Read more