In this blog post, I’ll feature work done by Vilela et al. with the NMReady-60 and illustrate how it can be used for on-line reaction monitoring and to optimize reaction conditions for the generation of singlet oxygen using BODIPY photosensitisers. Benchtop NMR 1-855-NMREADY (667-3239) toll-free in the US and Canada

One of the questions that we always get at tradeshows and conferences is how our instrument compares to high-field data. There are significant inherent differences between low-field and high-field instruments, but the most important from a chemistry point of view are sensitivity (S/N) and resonance dispersion (signal separation). Read More.

Nuclear magnetic resonance (NMR) is a critical tool for scientists undertaking structural elucidation or quantification of species in mixtures. Along with single crystal X-ray diffraction (SCXRD), no other technique provides as much information about a molecule’s conformation as NMR. This approach provides information about molecules in solution. Benchtop NMR 1-855-NMREADY (667-3239) toll-free in the US and Canada

2D NMR experiments can provide an abundance of information for the structural elucidation of chemical compounds. An older example of a 2D experiment is the heteronuclear correlation (HETCOR) sequence. In this experiment, two different nuclei (usually 13C and1H) are correlated through single bond spin-spin coupling, revealing which proton and carbon groups are bonded to each other.

In my opinion, one of the most helpful papers[1] in the field of NMR spectroscopy in Organic Chemistry consists of ‘just’ two tables. In these, the chemical shifts (1H and 13C) of as many as forty-two common impurities in twelve different deuterated solvents are listed. This is gold! Why?

Spin-spin coupling is an important facet of 1H NMR spectroscopy, as crucial details about the structure of a molecule are revealed based on the pattern of multiplets observed. Read more.

2D NMR experiments can provide a wealth of information to aid in the structural elucidation of chemical compounds. Of the many 2D NMR experiments available, the homonuclear correlation spectroscopy (COSY) sequence is one of the most popular and is used to identify which spin systems are directly coupled to each other. As an example, the 1H-1H COSY spectrum of 1-propanol recorded on the NMReady-60 is shown below in Figure 1.

…more and more analytical and industrial laboratories have started employing quantitative nuclear magnetic resonance (qNMR) spectroscopy as a tool for content assignment (due to its superb structural elucidation abilities) and quantification of purity in a sample. Read More.