Spin-spin coupling is an important facet of 1H NMR spectroscopy, as crucial details about the structure of a molecule are revealed based on the pattern of multiplets observed. In general, the signal for a group of equivalent protons will be split into a multiplet based on the n+1 rule, where nis the number of equivalent protons that are adjacent to the protons. For example, the signal of the CH2 protons in an ethyl group will be observed as a quartet (adjacent to three equivalent protons; 3+ 1) while the signal for the CH3protons in the same ethyl group will be a triplet (adjacent to two equivalent protons; 2+ 1).Read More
This important analytical tool can help chemists and other scientists analyze a sample's molecular structure without destroying the sample. As such, a 60 MHz benchtop NMR spectrometer is an invaluable tool in the modern laboratory.Read More
By using a technology called nuclear magnetic resonance (NMR) spectroscopy, scientists are able to see these molecules and magnify even their smallest details, observing how they behave in all types of matter.Read More
2D NMR experiments can provide a wealth of information to aid in the structural elucidation of chemical compounds. Of the many 2D NMR experiments available, the homonuclear correlation spectroscopy (COSY) sequence is one of the most popular and is used to identify which spin systems are directly coupled to each other. As an example, the 1H-1H COSY spectrum of 1-propanol recorded on the NMReady-60 is shown below in Figure 1.Read More
In this blog, Part III of the qNMR series, I will be addressing relaxation and why it's important for quantitative nuclear magnetic resonance (qNMR) experiments. If this is your first time reading about qNMR and would like to know more, please check out our other posts where you can find a general introduction to qNMR as well as information for the types of calibrants available for qNMR experiments.Read More
The fact that these new tools could provide information on the type of components in a molecule, their connectivity, and the quantity was great news for scientists. Over the years, there have been several modifications that make them even better. Here is how you can use the benchtop NMR to improve your workflow.
Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed more here.Read More
The textile industry is among the largest industries in the world. With global supply chains and a variety of products that is virtually unlimited, the difference between profitability and going under can be a slight increase in efficiency. One of the most important aspects of the textile process is using liquid coatings to coat fibers and manipulate their properties. These coatings are carefully formulated, and they usually contain numerous components.Read More