Welcome to Nanalysis’ benchtop NMR Blog
We love benchtop NMR! In this blog section, you will find all things benchtop NMR. Please contact us if you would like to discuss about your project.
Category
NMR Topics
- 100 MHz NMR
- 11B NMR
- 129Xe NMR
- 13C NMR
- 19F NMR
- 19F NMR Spectroscopy
- 1H NMR
- 31P NMR
- 3H NMR
- APT
- Agrochemicals
- Applications
- Batteries
- Biopolymers
- Botanicals
- COSY
- CPMG
- Cannabis
- Chemical Analysis
- Cosmetics
- DEPT
- Dithiazine
- Drug Analysis
- Dyes
- Edible Oils
- Educational NMR
- Energy
- Exchangeable Protons
- Exchangeable protons
- Flavor and Fragrances
- Flow NMR
- Fluorine-19 NMR
- Food Science
- Food and Beverage
- Forensics
- Forestry
- HMBC
- HSQC
- Hands-on Learning
- Heteronuclear J-coupling
- Hydrogen sulfide
- Hydroxyl value
- Hyphenated NMR
- Illicit Drugs
- Industrial Applications
- Inorganic Chemistry
- Interpretation of NMR
- Interpretation of NMR Spectra
- Inversion-Recovery
- Keto-Enol Tautomerism
Green Chemistry with Benchtop NMR
In this blog, we showcase how benchtop NMR is an accessible and versatile tool for chemists and non-chemists to evaluate greener methods.
What to expect from the tert-butanol 1D and 2D 13C NMR analysis?
Proton and carbon NMR analyses are routinely used in organic laboratories. In proton, 1H-1H coupling pattern is well exploited, and 1H-13C couplings as referred to as the carbon satellites. However, when acquiring carbon data, proton decoupling is applied most of the time and consequently it is not common to evaluate 1H-13C couplings in routine carbon analysis. This blog discusses the 1H-13C coupling in tert-butanol through 1D and 2D data, highlighting the key info. Read more.
NOESY: the experiment for when you just need to know more, particularly the 1H-1H spatial proximity
Given the superior resolution of our 100 MHz instrument, we can perform structure elucidation on increasingly large molecules. As molecules get more complex, as do the suite of experiments that can be used to…
DEPT: A tool for 13C peak assignments
Distortionless Enhancement by Polarization Transfer (DEPT) is a double resonance pulse program that transfers polarization from an excited nucleus to another – most commonly 1H → 13C. This results in a sensitivity enhancement relative to the standard decoupled 1D carbon spectra (13C), which benefits only from the small Nuclear Overhauser Effect (NOE) enhancements.
β-Diketone (Beta-diketone) tautomerization ratio determined via 60 MHz benchtop NMR
Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed…
DEPT: A tool for 13C peak assignments
Distortionless Enhancement by Polarization Transfer (DEPT) is a double resonance pulse program that transfers polarization from an excited nucleus to another – most commonly 1H → 13C. This results in a sensitivity enhancement relative to the standard decoupled 1D carbon spectra (13C), which benefits only from the small Nuclear Overhauser Effect (NOE) enhancements.
β-Diketone (Beta-diketone) tautomerization ratio determined via 60 MHz benchtop NMR
Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed…
Roses are red, violets are blue, hey look this COSY is cool
As Valentine’s Day approaches, I decided to analyze the 1H nuclear magnetic resonance (NMR) spectrum of the main aromatic component of roses, carnations, violets, lilies and chrysanthemums, which were b-damascenone, eugenol, b-ionone, linalool and a-pinene, respectively.
Two solvents, two different spectra - Aromatic Solvent Induced Shifts
In my opinion, one of the most helpful papers[1] in the field of NMR spectroscopy in Organic Chemistry consists of ‘just’ two tables. In these, the chemical shifts (1H and 13C) of as many as forty-two common impurities in twelve different deuterated solvents are listed. This is gold! Why?
NOESY: the experiment for when you just need to know more, particularly the 1H-1H spatial proximity
Given the superior resolution of our 100 MHz instrument, we can perform structure elucidation on increasingly large molecules. As molecules get more complex, as do the suite of experiments that can be used to…